Research Description

My research aims to utilize single-cell transcriptomics, optogenetic/chemogenetic techniques, and recombinase driver mice to characterize unique neuronal subpopulations within the hypothalamus and brainstem involved in the homeostatic regulation of appetite, thirst, and other autonomic functions.

Awards

• Fellowship Appointment on the Pharmacological Sciences Training Program (T32 GM144636), 2022-2024

• Dr. Lois Gehring Scholarship For academic and research excellence, 2022

Publications

• Li Y, Butler T, Nardone S, Jacobs C, Madara J, McDonough M, Tao J, Lowenstein E, Wang L, Pant D, Walker S, Wang A, Srinivasan H, Yang Z, Campbell J, Tsai L, Lowell B, Resch J. A spatial and projection-based transcriptomic atlas of paraventricular hypothalamic cell types, 21 October 2025, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-7895391/v1]. (Submitted to Nature Neuroscience)

• Ding, X., Weber, M.A., Butler, T.C., Bova, A.S., Guerrero, S., Hunter, C., Cole, R.C., Stutt, H.R., McMurrin, M., Spicer, M.M., Conlon, M.M., Heiney, S.A., Resch, J.M., Narayanan, N.S.  Diverse activity in prefrontal projtions promotes temporal control of action. bioRxiv [Preprint]. 2025 May 13:2025.05.12.653607. doi: 101/2025.05.12.653607, PMCID: PMC12132394

• Laule C, Guo DF, Zhao Y, Williams PA, Morgan DA, Rouabhi Y, McDonough M, Butler T, Resch J, Rahmouni K. The brainstem BBSome regulates glucose homeostasis and lean mass in a state-dependent manner. Mol Metab. 2025 Oct;100:102222. doi: 10.1016/j.molmet.2025.102222. Epub 2025 Jul 29. PMID: 40744313; PMCID: PMC12361606

• Butler, T.C., Zhang, J., Zhang, H., Ryu, S., & Greene, A.S.  Magnetic Patterning of Vorticella convallaria in a Microfluidic Device. J Eukaryot Microbiol. 67(6):687-690, 2020.  PMID: 32702141