Kolling LJ, Chimenti MS, Marcinkiewcz CA. Spatial differences in gene expression across the dorsal raphe nucleus in a model of early Alzheimer's disease. J Alzheimers Dis. 2025 Jan;103(1):133-148. doi: 10.1177/13872877241299119. PMID: 39584353

Khan, A., Mulfaul, K. Choroidal macrophages in homeostasis, aging and age-related macular degeneration. Exp Eye Res. 2025 Jan:250:110159. PMID: 39577606 

Howe JR, Menda Y, Chandrasekharan C, Bellizzi AM, Quelle DE, O'Dorisio MS, Dillon JS. The University of Iowa Neuroendocrine Tumor Clinic. Endocr Pract. 2025 Jan;31(1):4-18. doi: 10.1016/j.eprac.2024.09.018. PMCID: PMC11700786

Shilyansky JS, Chan CJ, Xiao S, Gribovskaja-Rupp I, Quelle DE, Howe JR, Dillon JS, Ear PH. GLP-1R agonist promotes proliferation of neuroendocrine neoplasm cells expressing GLP-1 receptors. Surgery. 2025 Mar 10:108943. doi: 10.1016/j.surg.2024.09.052. PMID: 39665969

Sakamoto K, Butera MA, Zhou C, Maurizi G, Chen B, Ling L., Shawkat A, Patlolla L, Thakker K, Calle V., Morgan DA, Rahmouni K, Schwartz G.J, Tahiri A, Buettner C. Overnutrition causes insulin resistance and metabolic disorder through increased sympathetic nervous system activity.  Cell Metab. 2025 Jan 7;37(1):121-137.e6. doi: 10.1016/j.cmet.2024.09.012. PMCID: PMC11711004

Laule C, Rahmouni K. Leptin and Associated Neural Pathways Underlying Obesity-Induced Hypertension. Comprehensive Physiology https://doi.org/10.1002/cph4.8

Siva M, Das K, Rana P, Saha A, Mandal D, Barik A, Stewart A, Maity B, Das P. Liposomal Encapsulation of Chlorambucil with a Terpyridine-Based, Glutathione-Targeted Optical Probe Facilitates Cell Entry and Cancer Cell Death. ACS Appl Bio Mater. 2025 Jan 20;8(1):570-581. doi: 10.1021/acsabm.4c01448. PMID: 39686811

Sandal, P., Jong, CJ., Merrill, R., Kollman, G., Paden, A., Bend, E., Sullivan, J., Spillmann, R., Shashi, V., Vulto-van Silfhout, A., Pfundt, R., de Vries, B., Li, P., Bicknell, L., Strack, S. De novo missense variants in the PP2A regulatory subunit PPP2R2B in a neurodevelopmental syndrome: potential links to mitochondrial dynamics and spinocerebellar ataxias. Hum Molec Genet 2025 Jan 29;34(2):117-127. PMCID: PMC11780858  [Made the Cover]

Bjorkman SH, Marti A, Jena J, García-Peña LM, Weatherford ET, Kato K, Koneru J, Chen J, Sood A, Potthoff MJ, Adams CM, Abel ED, Pereira RO. ATF4 expression in thermogenic adipocytes is required for cold-induced thermogenesis in mice via FGF21-independent mechanisms. Sci Rep. 2024 Jan 18;14(1):1563. doi: 10.1038/s41598-024-52004-8. https://pubmed.ncbi.nlm.nih.gov/38238383/

Bahl E, Chatterjee S, Mukherjee U, Elsadany M, Vanrobaeys Y, Lin L.-C, McDonough M, Giese KP, Resch J, Abel T, Michaelson JJ. (2024) NEUROeSTIMator: Using deep learning to quantify neuronal activation from single-cell and spatial transcriptomic data. Nature Communications, in press.doi: https://doi.org/10.1101/2022.04.08.487573

Oliveira MM, Mohamed M, Elder MK, Banegas-Morales K, Mamcarz M, Lu EH, Golhan EAN, Chatterjee S, Abel T. and Klann E. (2024). The integrated stress response effector GADD34 is repurposed by neurons to promote stimulus-induced translation. Cell Reports 43(2):113670. doi: 10.1016/j.celrep.2023.113670. Online ahead of print. PMCID: In process.

Evans MM, Kim J, Abel T, Nickl-Jockschat T, Stevens HE. Developmental Disruptions of the Dorsal Striatum in Autism Spectrum Disorder. Biol Psychiatry. 2024 Jan 15;95(2):102-111. doi: 10.1016/j.biopsych.2023.08.015. Epub 2023 Aug 29. PMID: 37652130 Review.

Kim, J., Vanrobaeys, Y., Peterson, Z., Kelvington, B., Gaine, M. E., Nickl-Jockschat, T. and Abel, T. (2024). Dissecting 16p11.2 hemi-deletion to study sex-specific striatal phenotypes of neurodevelopmental disorders. Molecular Psychiatry, 2024 Jan. In press. doi: https://doi.org/10.1101/2023.02.09.527866.

Kelvington, B and Abel, T. (2024). Innate immunity in neurons makes memories persist. Nature 628:40-42. PMCID: In process

Benjamin-Zukerman, T.^#, Shimon, G.^#, Gaine, M. E.^#, Dakwar, A., Peled, N., Aboraya, M., Masri-Ismail, A., Safadi-Safa, R., Solomon, M., Lev-Ram, V., Rissman, R. A., Mayrhofer, J. E., Raffeiner, A., Mol, M. O., Argue, B. M. R., McCool, S., Doan, B., van Swieten, J., Stefan, E., Abel, T.^#, and Ilouz, R.# (2024). A mutation in thePRKAR1B gene drives pathological mechanisms of neurodegeneration across species. Brain, awae154, https://doi.org/10.1093/brain/awae154 PMCID: In process. #contributed equally
           
Giri, B., Kaya, U., Maboudi, K., Abel, T. and Diba, K. (2024). Sleep loss diminishes hippocampal reactivation and replay. Nature 630: 935.  doi: 10.1038/s41586-024-07538-2 PMCID: PMC9949250.

Kim J, Vanrobaeys Y, Davatolhagh MF, Kelvington B, Chatterjee S, Ferri SL, Angelakos C, Mills AA, Fuccillo MV, Nickl-Jockschat T, Abel T. A chromosome region linked to neurodevelopmental disorders acts in distinct neuronal circuits in males and females to control locomotor behavior.  bioRxiv [Preprint]. 2024 May 17:2024.05.17.594746. doi: 10.1101/2024.05.17.594746. PMID: 38952795 Free PMC article. 

Mukherjee U, and Abel T. (2024). Molecular intersection of activity-dependent gene expression and behavior: The transcriptomic signature of long-term memory. In: Saha, R. N. and Dudek, S. M. (eds), Transcriptional regulation by neuronal activity: To the nucleus and back, 2nd Edition. pp. 433-468. Switzerland: Springer Nature. ISBN: 978-3-031-68549-1. //doi.org/10.1007/978-3-031-68550-7_14

Tadinada SM, Walsh EN, Mukherjee U, and Abel T. (2024) Differential effects of PDE4A5 on cAMP-dependent forms of long-term potentiation. J. Physiol., in press. PMCID: In Process. 

Laule C., Sayar-Atasoy N., Aklan I., Kim H., Ates T., Davis D., Atasoy D. Stress integration by an ascending adrenergic-melanocortin circuit. Neuropsychopharmacology. Feb 7. PMID: 38326456 doi: 10.1038/s41386-024-01810-9.

Agus S. Yavuz Y., Atasoy D., Yilmaz B. Post-weaning social isolation alters puberty onset by suppressing electrical activity of arcuate kisspeptin neurons. Neuroendocrinology. PMID: 38271999 doi: 10.1159/000535721

Baser O., Yavuz Y., Ozen D.O., Ozgun H.B., Agus S., Civas C.C., Atasoy D., Yılmaz B. Effects of Chronic High Fat Diet on Mediobasal Hypothalamic Satiety Neuron Function in POMC-Cre Mice. Molecular Metabolism doi.org/10.1016/j.molmet.2024.101904

Sayar-Atasoy N.*, Yavuz Y.*, Laule C., Dong C., Kim H., Rysted J., Flippo K., Davis D., Aklan I., Yilmaz B., Tian L., Atasoy D. Opioidergic signaling contributes to food-mediated suppression of AgRP neurons. Cell Reports 2024 Jan 1;43(1):113630. PMID: 38165803 doi: 10.1016/j.celrep.2023.113630.

Dong C, Gowrishankar R, Jin Y, He XJ, Gupta A, Wang H, Sayar-Atasoy N, Flores RJ, Mahe K, Tjahjono N, Liang R, Marley A, Or Mizuno G, Lo DK, Sun Q, Whistler JL, Li B, Gomes I, Von Zastrow M, Tejeda HA, Atasoy D, Devi LA, Bruchas MR, Banghart MR, Tian L. Unlocking opioid neuropeptide dynamics with genetically encoded biosensors. Nature Neuroscience 2024 Jul 15. doi: 10.1038/s41593-024-01697-1. PMID: 39009835

Bahl E, Chatterjee S, Mukherjee U, Elsadany M,  Vanrobaeys Y, Lin LC, McDonough M, Resch J, Giese KP, Abel T, Michaelson JJ. Using Deep Learning to Quantify Neuronal Activation from Single-Cell and Spatial Transcriptomic Data. Nature Communications 2023 (Accepted).

Lyu C, Bhimani AK, Draus WT, Weigel R, Chen S. (2023) Active Gαi/o Mutants Accelerate Breast Tumor Metastasis via the c-Src Pathway. Molec and Cellular Biol, 2025 43:12, 650-663, DOI: 10.1080/10985549.2023.2285833

Lyu C, Vaddi PK, Elshafae S, Pradeep A, Ma D, Chen S. Unveiling RACK1: a key regulator of the PI3K/AKT pathway in prostate cancer development. Oncogene 2024 Nov 13. doi: 10.1038/s41388-024-03224-9. PMID: 39537875

Liu H, Qu N, Gonzalez NV, Palma MA, Chen H, Xiong J, Choubey A, Li Y, Li X, Yu M, Liu H, Tu L, Zhang N, Yin N, Conde KM, Wang M, Bean JC, Han J, Scarcelli NA, Yang Y, Saito K, Cui H, Tong Q, Sun Z, Wang C, Cai X, Lu L, He Y, Xu Y.J  A Light-Responsive Neural Circuit Suppresses Feeding. Neurosci. 2024 Jul 24;44(30):e2192232024. doi: 10.1523/JNEUROSCI.2192-23.2024.PMID: 38897723

Ahlers-Dannen KE, Yang J, Spicer MM, Fu D, DeVore A, Fisher RA.  A splice acceptor variant in RGS6 associated with intellectual disability, microcephaly, and cataracts disproportionately promotes expression of a subset of RGS6 isoforms. Journal of Human Genetics. 2024 Feb 9. https://doi.org/10.1038/s10038-024-01220-1.

Spicer MM, Yang J, Fu D, DeVore AN, Lauffer M, Atasoy NS, Atasoy D, Fisher RA. Regulator of G protein signaling 6 mediates exercise-induced recovery of hippocampal neurogenesis, learning, and memory in a mouse model of Alzheimer’s disease. Neural Regeneration Research, 2024, 20:1-13. doi.org/10.4103/

Spicer MM, Weber MA, Luo Z, Yang J, Narayanan NS, Fisher RA. Regulator of G protein signaling 6 (RGS6) in dopamine neurons promotes EtOH seeking, behavioral reward, and susceptibility to relapse Regulator of G protein signaling 6 (RGS6) in dopamine neurons promotes EtOH seeking, behavioral reward, and susceptibility to relapse. Psychopharmacology 2024 Jun 10. Doi: 10.1007/s00213-024-06631-8. Online ahead of print.

Nagalakshmi Balasubramanian, Thomas D. James, Govindhasamy Pushpavathi Selvakumar, Jessica Reinhardt, Catherine A. Marcinkiewcz. Repeated ethanol exposure and withdrawal alters angiotensin-converting enzyme 2 expression in discrete brain regions: Implications for SARS-CoV-2 neuroinvasion. Alcohol, Clinical and Experimental Research Volume 47, Issue 2 p. 219-239.

• Lakshmi was awarded the ACER Journal Award for Early Career Investigator Outstanding paper

Pierson, SR, Kolling LJ, James TD, Pushpavathi, SG, Marcinkiewcz CA. 2024. Serotonergic dysfunction may mediate the relationship between alcohol consumption and Alzheimer's disease. Pharmacological Research 203:107171.

Kolling LJ, Khan K, Wang R, Pierson SR, Hartman BD, Balasubramanian N, Guo DF, Rahmoumi K, Marcinkiewcz CA. 2024. Interaction of serotonin/GLP-1 circuitry in a dual preclinical model for psychiatric disorders and metabolic dysfunction. Psychiatry Research 337: 115951.

Pierson SR, Fiock KL, Wang R, Balasubramanian N, Reinhardt J, Khan KM, James TD, Hunter ML, Cooper BJ, Williamsen HR, Betters R, Deniz K, Lee G, Aldridge G, Hefti MM, Marcinkiewcz CA. 2024. Tau pathology in the dorsal raphe may be a prodromal indicator of Alzheimer’s disease. Molecular Psychiatry. Epub ahead of print. doi: 10.1038/s41380-024-02664-9

Vaughn H, Major H, Kadera E, Keck K, Dunham T, Qian Q, Brown B, Scott A, Bellizzi AM, Braun T, Breheny P, Quelle DE, Howe JR, Darbro B. Functional Copy-Number Alterations as Diagnostic and Prognostic Biomarkers in Neuroendocrine Tumors.  Int J Mol Sci. 2024 Jul 9;25(14):7532. doi: 10.3390/ijms25147532.PMID: 39062773 Free PMC article.

Swier VJ, White KA, Negrão de Assis PL, Johnson TB, Leppert HG, Rechtzigel MJ, Meyerholz DK, Dodd RD, Quelle DE, Khanna R, Rogers CS, Weimer JM.  NF1+/ex42del miniswine model the cellular disruptions and behavioral presentations of NF1-associated cognitive and motor impairment.  Clin Transl Sci. 2024 Jun;17(6):e13858. doi: 10.1111/cts.13858.PMID: 38932491 Free PMC article

Howe JR, Menda Y, Chandrasekharan C, Bellizzi AM, Quelle DE, O'Dorisio MS, Dillon JS. The University of Iowa Neuroendocrine Tumor Clinic. Endocrine Practice, 2024 Sep 28:S1530-891X(24)00693-1. doi: 10.1016/j.eprac.2024.09.018. PMID: 39349242

Xu T, Dillon JS, Maluccio MA, Quelle DE, Nash SH, Cho H, Limbach KE, Skill NJ, Bren-Mattison Y, O'Rorke MA. Peptide Receptor Radionuclide Therapy and clinical associations with renal and hematological toxicities and survival in patients with neuroendocrine tumors: an analysis from two U.S. medical centers J Cancer Res Clin Oncol, 2024 Nov 2; 150(11):485.  PMCID: PMC11531437

Ear P, Marinoni I, Dayton T, Guenter R, Quelle, D, et al.: NET Models Meeting 2024 white paper: the current state of neuroendocrine tumour research models and our future aspirations. Endocrine Oncology 2024 Dec 19;4(1):e240055. PMCID: PMC11737514

Guo DF, Williams P, Laule C, Seaby C, Zhang Q, al C Sheffield VC, Rahmouni K: POMC Neuron BBSome Regulation of Energy Balance is Independent of its Ciliary Function. Function (In press)

Younes R, Guo DF, Zhao Y, Rahmouni K^*: Metabolic Consequences of Skeletal Muscle- and Liver-Specific BBSome Deficiency. American Journal of Physiology-Metabolic Physiology 2023 (in press).

Alain J De Solis, Almudena Del Río-Martín, Jan Radermacher, Weiyi Chen, Lukas Steuernagel, Corinna A Bauder, Fynn R Eggersmann, Donald A Morgan, Anna-Lena Cremer, Michael Sué, Maximilian Germer, Christian Kukat, Stefan Vollmar, Heiko Backes, Kamal Rahmouni, Peter Kloppenburg, Jens C Brüning. Reciprocal activity of AgRP and POMC neurons governs coordinated control of feeding and metabolism. Nat Metab, 2024 Feb 20. doi: 10.1038/s42255-024-00987-z. Online ahead of print.

Rahmouni K. Neural Circuits Underlying Reciprocal Cardiometabolic Crosstalk: 2023 Arthur C. Corcoran Memorial Lecture.Hypertension. 2024 Mar 27. doi: 10.1161/HYPERTENSIONAHA.124.22066. Online ahead of print. PMID: 38533662

Qian Q, Li M, Zhang Z, Davis S, Rahmouni K, Norris AW, Cao H, Ding WX, Yang L Obesity Disrupts the Pituitary-Hepatic UPR Communication Leading to NAFLD Progression. Cell Metabolism (In press)

Faniyan TS, Zhang X, Morgan DA, Robles J, Bathina S, Brookes PS, Rahmouni K, Perry RJ, Chhabra KH. A kidney-hypothalamus axis promotes compensatory glucose production in response to glycosuria. Elife. 2024 Jul 31;12:RP91540. doi: 10.7554/eLife.91540.

Qian Q, Li M, Zhang Z, Davis S, Rahmouni K, Norris AW, Cao H, Ding WX, Yang L.: Obesity Disrupts the Pituitary-Hepatic UPR Communication Leading to NAFLD Progression. Cell Metabolism 2024; 36(7):1550-1565.e9.

Zhao Y, Guo DF, Morgan DA, Cho Y-E, Rahmouni K*.: Adipocyte-Specific Disruption of the BBSome Causes Metabolic and Autonomic Dysfunction. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2024; 327(1):R54-R65.

Sakamoto K, Butera MA, Zhou C,  Maurizi G, Chen B, Shawkat A, Patlolla L, Thakker K, Calle V, Morgan DA, Rahmouni K, Schwartz GJ, Tahiri A, Buettner C.: Overnutrition causes insulin resistance and metabolic disorder through increased sympathetic nervous system activity. Cell Metabolism (In press)

Nardone S, De Luca R, Zito A, Klymko N, Nicoloutsopoulos D, Amsalem O, Brannigan C, Resch JM, Jacobs CL, Pant D, Veregge M, Srinivasan H, Grippo RM, Yang Z, Zeidel ML, Andermann ML, Harris KD, Tsai LT, Arrigoni E, Verstegen AMJ, Saper CB, Lowell BB. A spatially-resolved transcriptional atlas of the murine dorsal pons at single-cell resolution. Nat Commun. 2024;15(1):1966. PubMed PMID: 38438345; PMCID: PMC10912765.

Kuralay A, McDonough MC, Resch JM. Control of sodium appetite by hindbrain aldosterone-sensitive neurons. Mol Cell Endocrinol. 2024;592:112323. PMID: 38936597.

Gasparini S, Peltekian L, McDonough MC, Mitchell CJ, Hefti M, Resch JM, Geerling JC. Aldosterone-induced salt appetite requires HSD2 neurons. JCI Insight. 24:e175087, 2024. PMID: 39446486

Gasparini S, Almeida-Pereira G, Munuzuri ASP, Resch JM, Geerling JC. Molecular Ontology of the Nucleus of Solitary Tract. J Comp Neurol. 2024 Dec;532(12):e70004. PMCID: PMC11615840

Cheng-Guo Wu, … Stefan Strack*, and Yongna Xinga*.: B56δ long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan’s syndrome mutations.  Proceeding of the National Academy of Sciences, (2023); 121(1):e2310727120.  *co-corresponding authors

Glebov-McCloud AGP, Saide WS, Gaine ME, Strack S. Protein Kinase A in neurological disorders. J Neurodev Disord. 2024 Mar 13;16(1):9. doi: 10.1186/s11689-024-09525-0

Hardy JC, Pool EH, Bruystens JGH, Zhou X, Li Q, Zhou DR, Palay M, Tan G, Chen L, Choi JLC, Lee HN, Strack S, Wang D, Taylor SS, Mehta S, Zhang. Molecular determinants and signaling effects of PKA RIα phase separation. Mol Cell. 2024 Mar 22:S1097-2765(24)00184-9. doi: 10.1016/j.molcel.2024.03.002. Online ahead of print. PMID: 38537638

Chen C, Merrill RA, Jong CJ, Strack S. Driving mitochondrial fission improves cognitive, but not motor deficits in a mouse model of Ataxia of Charlevoix-Saguenay. The Cerebellum (in press) (also Res Sq [Preprint]. 2024 Apr 10:rs.3.rs-4178088. doi: 10.21203/rs.3.rs-4178088/v1.PMID: 38659734)

Sandal P, Jong CJ, Merrill RA, Kollman GJ, Paden AH, Bend EG, Sullivan J, Spillmann RC, Shashi V, Vulto-van Silfhout AT, Pfundt R, de Vries BBA, Li PP, Bicknell LS, Strack S. De novo missense variants in the PP2A regulatory subunit PPP2R2B in a neurodevelopmental syndrome: potential links to mitochondrial dynamics and spinocerebellar ataxias. Hum Mol Genet. 2024 Nov 20:ddae166. doi: 10.1093/hmg/ddae166. Online ahead of print. PMID: 39565297

Leinheiser AK, Mitchell CC, Rooke E, Strack S, Grueter CE. A dynamical systems model for the total fission rate in Drp1-dependent mitochondrial fission. PLoS Comput Biol. 2024 Nov 18;20(11):e1012596. doi: 10.1371/journal.pcbi.1012596. Online ahead of print. PMID: 39556606

Brown EB, Zhang J, Lloyd E, Lanzon E, Botero V, Tomchik SM, Keene AC. Neurofibromin 1 mediates sleep depth in Drosophila. PLoS Genetics (accepted).

Villa, S. Dwivedi, P. Stahl, A. Rose, C., Kirkpatrick, D.S., Tomchik, S.M., Dixit, V.M., Wolf, F.W.  (2024) TUD6 deubiquitination of RPS7/eS7 on the free 40S ribosome regulates protein translation and the response to stress. Nat Commun 15: 6873.

Omana Suarez, G., Kumar, D.S., Brunner, H., Emel, J., Teel, J., Botero, V., Broyles, C., Stahl, A., Bidaye, S., Tomchik, S.M. (2024) Neurofibromin deficiency alters the patterning and prioritization of motor behaviors in a state-dependent manner. bioRxiv [preprint] doi: 10.1101/2024.08.08.607070.

Stahl, A., Tomchik, S.M. (2024) Modeling neurodegenerative and neurodevelopmental disorders in the Drosophila mushroom body. Learning and Memory 31: a053816.123.

Evans, M. M., Kim, J., Abel, T., Nickl-Jockschat, T. and Stevens, H. E. (2023). Developmental disruptions of the dorsal striatum in autism spectrum disorder, Biological Psychiatry, doi: https://doi.org/10.1016/j.biopsych.2023.08.015. PMCID: In Process.

Sengupta, A., Tudor, J, Cusmano, D., Baur, J. A., Abel, T. and Weljie, A. (2023). Sleep deprivation and aging are metabolically linked across tissues. Sleep, Sep 20:zsad246. doi: 10.1093/sleep/zsad246. Online ahead of print. PMCID: In process.

Vanrobaeys, Y., Peterson, Z. J., Walsh, E. N., Chatterjee, S., Lin, L.-C., Lisa C. Lyons, L. C., Nickl-Jockschat, T. and Abel, T. (2023). Spatial transcriptomics reveals unique gene expression changes in different brain regions after sleep deprivation. Published online. Nature Communications.  

Walsh, E. N., Shetty, M. S., Diba, K. and Abel, T. (2022). Chemogenetic enhancement of cAMP signaling renders hippocampal synaptic plasticity resilient to the impact of acute sleep deprivation, eNeuro, in press. PMCID in progress.

Casten, L.G., Thomas, T.R., Doobay, A.F., Foley-Nicpon, M., Kramer, S., Nickl-Jockschat, T., Abel, T, Assouline, S., Michaelson, J.J. (2022). The combination of autism and exceptional cognitive ability is associated with suicidal ideation. Neurobiology of Learning & Memory, in press.  PMCID in progress.

Sarinnapha M. Vasunilashorn, Nadia Lunardi, John C. Newman, Gregory Crosby, Leah Acker, Ted Abel, Seema Bhatnagar, Colm Cunningham, Rafael de Cabo, Laura Dugan, Joseph A. Hippensteel, Yumiko Ishizawa, Shouri Lahiri, Edward R. Marcantonio, Zhongcong Xie, Sharon K. Inouye, Niccolò Terrando, Roderic G. Eckenhoff, for the NIDUS Delirium Network. Preclinical and translational models for delirium: Recommendations for future research from the NIDUS delirium network. Alzheimer’s & Dementia (The Journal of the Alzheimer’s Association). 19(5):2150-2174, 2023. doi.org/10.1002/alz.12941

Benjamin A. Kelvington and Ted Abel. hnRNPH2 gain-of-function mutations reveal therapeutic strategies and a role for RNA granules in neurodevelopmental disorders.  J Clin Invest. 2023;133(14):e171499. https://doi.org/10.1172/JCI171499.

Laule C, Atasoy D. Hunger potentiated. Cell Metab. 2023 May 2;35(5):723-725. doi: 10.1016/j.cmet.2023.04.005. PMID: 37137283

Aklan I, Atasoy NS, Deng F, Kim H, Yavuz Y, Rysted J, Laule C, Davis D, Li Y, Atasoy D. Dorsal Raphe Serotonergic Neurons Suppress Feeding Through Redundant Forebrain Circuits. Molecular Metabolism 2023 Jan 19:101676. doi: 10.1016/j.molmet.2023.101676. PMID: 36682413

Balapattabi K., Yavuz Y., Jiang J., Deng G., Mathieu N.M., Ritter M.L., Opichka M.A., Reho M.J., Nakagawa P., Morselli L.L., Mouradian G.C., Atasoy D., Cui H., Hodges M.R., Sigmund C.D., Grobe J.L. Angiotensin AT1A receptor signal switching in Agouti-related peptide neurons mediates metabolic rate adaptation during obesity. Cell Reports 2023 Aug 2;42(8):112935. PMID: 37540598 doi:10.1016/j.celrep.2023.112935.

Fernandez G., De Francesco P.N., Cornejo M.P, Cabral A., Aguggia J., Victor Duque J., Sayar N., Cantel S., Burgos J.I., Fehrentz J.A., Rorato R., Atasoy D., Mecawi A., Perello M. Ghrelin action in the hypothalamic paraventricular nucleus of male mice: direct neuronal targets, accessibility and activation of the hypothalamic-pituitary-adrenal axis. Endocrinology 2023 Oct 12. PMID: 37823477. doi: 10.1210/endocr/bqad154 

Nilufer Sayar-Atasoy, Iltan Aklan, Yavuz Yavuz, Connor Laule, Hyojin Kim, Jacob Rysted, Muhammed Ikbal Alp, Debbie Davis, Bayram Yilmaz, Deniz Atasoy. AgRP neurons encode circadian feeding time. Nat Neurosc. 2023 Nov 13. doi: 10.1038/s41593-023-01482-6. Online ahead of print.

Sayar-Atasoy, N., Laule, C., Aklan, I., Kim, H., Yavuz, Y., Ates, T., Coban, I., Koksalar-Alkan, F., Rysted, J., Davis, D., Singh, U., Alp, M., Yilmaz, B., Cui, H., Atasoy, D.  Adrenergic modulation of melanocortin pathway by hunger signals. Open access. Nature Communications 14(1):6602, 2023

Vanrobaeys Y., Mukherjee U., Langmack L., Beyer SE., Bahl E., Lin LC., Michaelson JJ., Abel T.* and Chatterjee S*. Mapping the spatial transcriptomic signature of the hippocampus during memory consolidation. Nature Communications, 2023 Sept 29; 4, 6100. https://doi.org/10.1038/s41467-023-41715-7

Balapattabi K, Yavuz Y, Jiang J, Deng G, Mathieu NM, Ritter ML, Opichka MA, Reho JJ, McCorvy JD, Nakagawa P, Morselli LL, Mouradian GC Jr, Atasoy D, Cui H, Hodges MR, Sigmund CD, Grobe JL. Angiotensin AT1A receptor signal switching in Agouti-related peptide neurons mediates metabolic rate adaptation during obesity. Cell Rep. 2023 Aug 2;42(8):112935. doi: 10.1016/j.celrep.2023.112935. 

Singh U, Saito K, Khan MZ, Jiang J, Toth BA, Rodeghiero SR, Dickey JE, Deng Y, Deng G, Kim YC, Cui H. Collateralizing ventral subiculum melanocortin 4 receptor circuits regulate energy balance and food motivation. Physiol Behav. 2023 Apr 1;262:114105. doi: 10.1016/j.physbeh.2023.114105. Epub 2023 Feb 1. PMID: 36736416

Saito K and Cui H. Estrogen Receptor Alpha Splice Variants, Post-Translational Modifications, and Their Physiological Functions. Cells. 2023, 12(6), 895.

Wagner VA, Deng G, Claflin KE, Ritter ML, Cui H, Nakagawa P, Sigmund CD, Morselli LL, Grobe JL, Kwitek AE. Cell-specific transcriptome changes in the hypothalamic arcuate nucleus in a mouse deoxycorticosterone acetate-salt model of hypertension. Front Cell Neurosci. 2023 May 24;17:1207350. doi: 10.3389/fncel.2023.1207350.

Jianqi Yang, Alison N. DeVore, Daniel A. Fu, Mackenzie M. Spicer, Mengcheng Guo, Samantha G. Thompson, Katelin E. Ahlers-Dannen, Federica Polato, Andre Nussenzweig, and Rory A. Fisher.  “Rapid and precise genotyping of transgene zygosity in mice using an allele-specific method”.  Life Science Alliance (accepted).

Kanza Khan; Nagalakshmi Balasubramanian; Gabriel Gaudencio; Ruixiang Wang; Govindhasamy Selvakumar; Louis Kolling; Samantha Pierson; Satya Tadinada; Ted Abel; Marco Hefti; Catherine Marcinkiewcz. Human tau-overexpressing mice recapitulate brainstem involvement and neuropsychiatric features of early Alzheimer’s disease. Acta Neuropathologica Communications.

Kohlmeyer JL, Lingo JJ, Kaemmer CA, Scherer A, Warrier A, Voigt E, Raygoza Garay JA, McGivney GR, Brockman QR, Tang A, Calizo A, Pollard K, Zhang X, Hirbe AC, Pratilas CA, Leidinger M, Breheny P, Chimenti MS, Sieren JC, Monga V, Tanas MR, Meyerholz DK, Darbro BW, Dodd RD, Quelle DE. CDK4/6-MEK inhibition in MPNSTs causes plasma cell infiltration, sensitization to PD-L1 blockade, and tumor regression.  Clin Cancer Res. 2023 Jul 6:CCR-23-0749. doi: 10.1158/1078-0432.CCR-23-0749. Online ahead of print. PMID: 37410426

Voigt E, Quelle DE. FOXM1, MEK, and CDK4/6: New Targets for Malignant Peripheral Nerve Sheath Tumor Therapy. Int J Mol Sci. 2023 Sep 2;24(17):13596. doi: 10.3390/ijms241713596.PMID: 37686402 Free PMC article. Review.

Kohlmeyer JL, Lingo JJ, Kaemmer CA, Scherer A, Warrier A, Voigt E, Raygoza Garay JA, McGivney GR, Brockman QR, Tang A, Calizo A, Pollard K, Zhang X, Hirbe AC, Pratilas CA, Leidinger M, Breheny P, Chimenti MS, Sieren JC, Monga V, Tanas MR, Meyerholz DK, Darbro BW, Dodd RD, Quelle DE. CDK4/6-MEK Inhibition in MPNSTs Causes Plasma Cell Infiltration, Sensitization to PD-L1 Blockade, and Tumor Regression. Clin Cancer Res. 2023 Sep 1;29(17):3484-3497. doi: 10.1158/1078-0432.CCR-23-0749.PMID: 37410426

Stump M, Guo DF, Rahmouni K.: T Cell-Specific Deficiency in BBSome Component BBS1 Interferes with Selective Immune Responses. Am J Physiol Regul Integr Comp Physiol. 2022 Dec 19. doi: 10.1152/ajpregu.00243.2022. Online ahead of print.PMID: 36534590

Guo DF, Merrill RA, Qian L, Hsu Y, Zhang Q, Lin Z, Thedens DR, Usachev YM, Grumbach I, Sheffield VC, Strack S, Rahmouni K.: The BBSome regulates mitochondria dynamics and function. Mol Metab. 2022 Dec 10;67:101654. doi: 10.1016/j.molmet.2022.101654. Online ahead of print.PMID: 3651322 

Ye Y, Abu El Haija M, Obeid R, Herz H, Tian L, Linden B, Chu Y, Guo DF, Levine DC, Cedernaes J, Rahmouni K, Bass J, Mokadem M. Gastric bypass alters diurnal feeding behavior and reprograms hepatic clock to regulate endogenous glucose flux. JCI Insight. 2023 Feb 14:e166618. doi: 10.1172/jci.insight.166618. Online ahead of print.PMID: 36787197 Free article.

Arnold AC, Rahmouni K. Methods and applications in metabolic physiology. Front Physiol. 2023 Feb 9;14:1156826. doi: 10.3389/fphys.2023.1156826. eCollection 2023. PMID: 36846341 Free PMC article. No abstract available.

Peltekian L*, Gasparini S*, Fazan FS, Karthik S, Iverson G, Resch JM, Geerling JC. Sodium appetite and thirst do not require angiotensinogen production in astrocytes or hepatocytes. J Physiol. 2023;601(16):3499-532. PMID: 37291801

Douglass AM*, Resch JM*, Madara JC*, Kucukdereli H, Yizhar O, Grama A, Yamagata M, Yang Z, Lowell BB. Neural basis for fasting activation of the hypothalamic-pituitary-adrenal axis. Nature. 2023;620(7972):154-62. PMID: 37495689

Boto T, Tomchik SM. Ex Vivo Brain Imaging in Drosophila. Cold Spring Harb Protoc. 2023 May 17. doi: 10.1101/pdb.prot108136. Online ahead of print. PMID: 37197828

Boto T, Tomchik SM. Imaging Olfactory Learning-Induced Plasticity in Vivo in the Drosophila Brain. Cold Spring Harb Protoc. 2023 May 17. doi: 10.1101/pdb.prot108135. Online ahead of print. PMID: 37197829

Boto T, Tomchik SM. Functional Imaging of Learning-Induced Plasticity in the Central Nervous System with Genetically Encoded Reporters in Drosophila. Cold Spring Harb Protoc. 2023 May 17. doi: 10.1101/pdb.top107799. Online ahead of print. PMID: 37197830

Walters G.S., Usachev Y.M. (2023). Mitochondrial Calcium Cycling in Neuronal Function and Neurodegeneration. Frontiers in Cell and Developmental Biology,. doi: 10.3389/fcell.2023.1094356 .

Ghatge, M., Nayak M.K., Flora G.D., Kumskova M., Jain A., Patel, R.B., Lin Z., Usachev Y.M., Chauhan A.K. (2023) Mitochondrial Calcium Uniporter B deletion inhibits platelet function and reduces susceptibility to arterial thrombosis. Journal of Thrombosis and Haemostasis. 
doi: 10.1016/j.jtha.2023.04.002. PMID: 37061131   

Bolsius YG, Meerlo P, Kas MJ, Abel T, Havekes R. Sleep deprivation reduces the density of individual spine subtypes in a branch-specific fashion in CA1 neurons. J Sleep Res. 2022 Feb;31(1):e13438. doi: 10.1111/jsr.13438. Epub 2021 Jul 15.

Doldur-Balli F,Imamura T, Veatch OJ, Gong NN, Lim DC, Hart MP, Abel T, Kayser MS, Brodkin ES, Pack AI.  Synaptic dysfunction connects autism spectrum disorder and sleep disturbances: A perspective from studies in model organisms. Sleep Med Rev. 2022 Jan 25;62:101595. Doi: 10.1016/j.smrv.2022.101595 [Review]

Jill L. Silverman, Audrey Thurm, Sarah B. Ethridge, Makayla M. Soller, Stela P. Petkova, Ted Abel, Melissa D. Bauman, Edward S. Brodkin, Hala Harony-Nicolas, Markus Wöhr, Alycia Halladay. Reconsidering animal models used to study autism spectrum disorder: Current state and optimizing future. Genes, Brain and Behavior, 14 March 2022, https://doi.org/10.1111/gbb.12803

Emily Nicole Walsh, Mahesh Shivarama Shetty, Kamran Diba, Ted Abel. Chemogenetic enhancement of cAMP signaling renders hippocampal synaptic plasticity resilient to the impact of acute sleep deprivation. bioRxiv 2022, doi: https://doi.org/10.1101/2022.03.11.483982

Shetty MS, Ris L, Schindler RFR, Mizuno K, Fedele L, Giese KP, Brand T, Abel T. Mice Lacking the cAMP Effector Protein POPDC1 Show Enhanced Hippocampal Synaptic Plasticity.  Cereb Cortex. 2022 Aug 3;32(16):3457-3471. doi: 10.1093/cercor/bhab426.PMID: 34937090 

Stubbs T., Koemeter-Cox A., Bingman J.I., Zhao F., Kalyanasundaram A., Rowland L.A., Periasamy M., Carter C.S., Sheffield V.C., Askwith C.C., Mykytyn K. Disruption of dopamine receptor 1 localization to primary cilia impairs signaling in striatal neurons. Journal of Neuroscience. 2022.

Huang S.H., Pak T.K., Graber C.P., Searby C.C., Liu G., Marcy J., Yaszemski A.K., Bedell K., Bui E., Perlman S., Zhang Q., Wang K., Sheffield V.C. and Carter C.S.: An open source and convenient method for the wide-spread testing of COVID-19 using deep throat sputum samples. PeerJ. 2022.

Lyu C, Ye Y, Weigel RJ, Chen S. Blocking Gi/o-Coupled Signaling Eradicates Cancer Stem Cells and Sensitizes Breast Tumors to HER2-Targeted Therapies to Inhibit Tumor Relapse.  Cancers (Basel). 2022 Mar 28;14(7):1719. doi: 10.3390/cancers14071719.PMID: 35406489 

Yue Deng, Jacob E. Dickey, Kenji Saito, Guorui Deng, Uday Singh, Jingwei Jiang, Brandon A. Toth, Zhiyong Zhu, Leonid V. Zingman, Jon M. Resch, Justin L. Grobe, Huxing Cui. Elucidating the role of Rgs2 expression in the PVN for metabolic homeostasis in mice. Mol Metab (accepted)

Ritter ML, Deng G, Reho JJ, Deng Y, Sapouckey SA, Opichka MA, Balapattabi K, Wackman KK, Brozoski DT, Lu KT, Paradee WJ, Gibson-Corley KN, Cui H, Nakagawa P, Morselli LL, Sigmund CD, Grobe JL. Cardiometabolic Consequences of Deleting the Regulator of G protein Signaling-2 (Rgs2) From Cells Expressing Agouti-Related Peptide or the ANG (Angiotensin) II Type 1A Receptor in Mice. Hypertension. 2022 Oct 19. doi: 0.1161/HYPERTENSIONAHA.122.20169

Saito K, Dickey JE, Rodeghiero SR, Toth BA, Kelly MJ, Deng Y, Singh U, Deng G, Jiang J, Cui H. Hypomorphism of a novel long ERα isoform causes severe reproductive dysfunctions in female mice. Endocrinology. 2022 Oct 1:bqac160. doi: 10.1210/endocr/bqac160. Online ahead of print.

Zhou B, Claflin KE, Flippo KH, Sullivan AI, Asghari A, Tadinada SM, Jensen-Cody SO, Abel T, Potthoff MJ. Central FGF21 Production Regulates Memory but Not Peripheral Metabolism. Cell Reports. 2022 Aug 23;40(8):111239. doi: 10.1016/j.celrep.2022.111239. https://pubmed.ncbi.nlm.nih.gov/36001982/

Claflin KE, Sullivan AI, Naber MC, Flippo KH, Morgan DA, Neff TJ, Jensen-Cody SO, Zhu Z, Zingman LV, Rahmouni K, Potthoff MJ. Pharmacological FGF21 Signals to Glutamatergic Neurons to Enhance Leptin Action and Lower Body Weight Through Increases in Energy Expenditure During Obesity. Molecular Metabolism. 2022 Aug 6;101564. doi: 10.1016/j.molmet.2022.101564. https://pubmed.ncbi.nlm.nih.gov/35944896/ 

Pereira RO, Olvera AC, Marti A, Fang S, White JR, Westphal M, Hewezi R, AshShareef ST, Pena LMG, Koneru J, Potthoff MJ, Abel ED. OPA1 Regulates Lipid Metabolism and Cold-Induced Browning of White Adipose Tissue in Mice.  Diabetes. 2022 Sep 28:db220450. doi: 10.2337/db22-0450. Online ahead of print. PMID: 36170659

Kohlmeyer JL, Kaemmer CA, Lingo JJ, Voigt E, Leidinger MR, McGivney GR, Scherer A, Koppenhafer SL, Gordon DJ, Breheny P, Meyerholz DK, Tanas MR, Dodd RD, Quelle DE.:  Oncogenic RABL6A promotes NF1-associted MPNST progression in vivo. Neurooncol Adv. 2022 Apr 9;4(1):vdac047. doi: 10.1093/noajnl/vdac047. eCollection 2022 Jan-Dec. 

Shi Fang, Jing Wu, John J. Reho, Ko-Ting Lu, Daniel T. Brozoski, Gaurav Kumar, Alec M. Werthman, Sebastiao Donato Silva Jr, Patricia C. Muskus Veitia, Kelsey K. Wackman, Angela J Mathison, Bi Qing Teng, Chien-Wei Lin, Frederick W. Quelle, and Curt D. Sigmund.: RhoBTB1 reverses established arterial stiffness in angiotensin-II hypertension by promoting actin depolymerization. JCI insight. 2022. https://doi.org/10.1172/jci.insight.158043. 

Meyerholz DK, Leidinger MR, Goeken JA, Businga TR, Akers A, Vizuett S, Kaemmer CA, Kohlmeyer JL, Dodd RD, Quelle DE. Utility of CD138/syndecan-1 immunohistochemistry for localization of plasmacytes is tissue-dependent in B6 mice.  BMC Res Notes. 2022 Jun 25;15(1):219. doi: 10.1186/s13104-022-06100-5.PMID: 35752869

Gutierrez WR, Scherer A, Rytlewski JD, Laverty EA, Sheehan AP, McGivney GR, Brockman QR, Knepper-Adrian V, Roughton GA, Quelle DE, Gordon DJ, Monga V, Dodd RD. Augmenting chemotherapy with low-dose decitabine through an immune-independent mechanism. JCI Insight. 2022 Oct 13:e159419. doi: 10.1172/jci.insight.159419. Online ahead of print. PMID: 36227698 

Sedlack AJH, Saleh-Anaraki K, Kumar S, Ear PH, Lines KE, Roper N, Pacak K, Bergsland E, Quelle DE, Howe JR, Pommier Y, Del Rivero J. Preclinical Models of Neuroendocrine Neoplasia. Cancers (Basel). 2022 Nov 17;14(22):5646. doi: 10.3390/cancers14225646. PMID: 36428741

Rahmouni, K.: Energy metabolism and syncope. Editorial, Clin Auton Res. 2022 Dec;32(6):391-393. doi: 10.1007/s10286-022-00906-w. Epub 2022 Nov 3. 

Walters GC, Usachev YM. MCU (Mitochondrial Ca2+ Uniporter) makes the calcium go round, Journal of Biological Chemistry (2022), doi: https://doi.org/10.1016/j.jbc.2022.101604. [JBC EDITORS' PICK HIGHLIGHT]

Klomp A, Omichi R, Iwasa Y, Smith RJ, Usachev YM, Russo AF, Narayanan NS, Lee A. The voltage-gated Ca2+ channel subunit α2δ-4 regulates locomotor behavior and sensorimotor gating in mice. PLoS One. 2022 Mar 30;17(3):e0263197. doi: 10.1371/journal.pone.0263197. eCollection 2022. PMID: 3535383