Research Description

Identifying genetic modifiers and treatments for LMNA-associated striated muscle laminopathies

Awards

• American Heart Association Predoctoral Fellowship (25PRE1373209), 2025-2026
• American Society for Cell Biology Cell Bio Meeting Travel Grant, October 2025
• Graduate Student Senate Travel Grant Recipient, March 2024

• Institutional Fellowship on the Predoctoral Training Grant in the Pharmacological Sciences (T32 GM146636), 2023-2024

• Predoctoral Training Grant in the Pharmacological Sciences (T32 GM144636), 2022-2023

Publications

• Mayer, S.M., Christensen, Q.H., McCoy-Munger, H., Mohar, N.P., Botero, V., Tomchik, S., Drack, A.V., Wallrath, L.L. (2025). N-acetylcysteine suppresses retinal defects in Drosophila models of SNRNP200-associated Retinitis Pigmentosa. Redox Biology. In revision.

• Mohar, N.P., Langland, C.J., Darr, Z., Viles, J., Moore, S.A., Darbro, B.W., & Wallrath, L.L. (2025). A genetic variant in SMAD7 acts as a modifier of LMNA-associated muscular dystrophy, implicating SMAD signaling as a therapeutic target. Sci. Adv. 11, eads7903 (2025). DOI:10.1126/sciadv.ads7903

• Mohar NP, Cox EM, Adelizzi E, Moore SA, Mathews KD, Darbro BW, Wallrath LL. The Influence of a Genetic Variant in CCDC78 on LMNA-Associated Skeletal Muscle Disease. International Journal of Molecular Sciences. 2024; 25(9):4930. https://doi.org/10.3390/ijms25094930