Research Description

Investigating the Spatial Coordination of Actin Cytoskeleton Reinforcement and Glycolysis

Awards

• American Heart Association Predoctoral Fellowship (25PRE1365873), 2025-2026
• Predoctoral Training Grant in the Pharmacological Sciences (T32 GM144636), 2022-2024

Publications

Cronin, N.M., Dawson, L.W., DeMali, K.A.  Mechanical activation of VE-cadherin stimulates AMPK to increase endothelial cell metabolism and vasodilation. bioRxiv [Preprint]. 2024 May 13:2024.05.09.593171. doi: 10.1101/2024.05.09.593171.  PMCID: PMC11118335

Cronin, N.M., Dawson, L.W., DeMali, K.A.  Shear stress-stimulated AMPK couples endothelial cell mechanics, metabolism and vasodilation. J Cell Sci. 2024 Dec 15;137(24):jcs262232. doi: 10.1242/jcs.262232. Epub 2024 Dec 18.  PMCID: PMC11795286

DeWane, G., Cronin, N.M., Dawson, L.W., Heidema, C., DeMali, K.A.  Vinculin Y822 is an important determinant of ligand binding. J. Cell Sci. 2023 Jun 15;136(12):jcs260104. doi: 10.1242/jcs.260104. Epub 2023 Jun 14.  PMCID: PMC10281268

Dawson, L.W., Cronin, N.M., DeMali, K.A.  Mechanotransduction: Forcing a change in metabolism. Curr Opin Cell Biol. 2023 Oct;84:102219. doi: 10.1016/j.ceb.2023.102219. Epub 2023 Aug 29.  PMCID: PMC10523412 (Review)